research

Surgeons at UC Irvine have been responsible for many new technologies and therapies to improve healthcare. In fact, UC Irvine is ranked among the top 50 U.S. medical schools for research and primary care, according to U.S. News & World Report rankings.

UC Irvine’s Department of Surgery conducts basic research and industry-supported clinical and basic research studies. Committed to remaining at the leading edge of these and many other research efforts, including the exponentially expanding field of cell transplantation, tissue preservation, cell processing and expansion.

We welcome your interest in our research activities and are committed to helping medical students, surgical trainees and young investigators establish mentoring relationships with our faculty. If you are interested in the research activities occurring within our department, please contact David Hoyt, M.D., dhoyt@uci.edu, or Jonathan Lakey, Ph.D., jlakey@uci.edu.

Current Basic Research Studies

• Hypertonic Resuscitation Following Traumatic Injury
• Development of Bio-Artificial Pancreas for Diabetes
  
• Efficacy of Radiation and Sunitinib on Cancer and Stroma in Pancreas Cancer
• Enhancing Islet Cell Survival by Inhibiting Apoptosis
• Imaging Pancreatic Islets In-Vivo
• The Inflammatory Response to Brain Death
• The evaluation of enteral protease inhibitor for shock

Current Clinical Research Studies

• Participation in the Research Outcomes Consortium (ROC) Hypertonic Saline for TBI Study
• Prospective SICU DVT Prevention Study with an Emphasis on Low Molecular Weight Heparin Dosing
• Participation in the American Association for the Surgery of Trauma (AAST) Multi-Center Studies
• Retrospective Trauma and Burn Registry Studies
• The Relationship Between Parenteral Nutrition, Hyperglycemia and Nosocomial Infections in the SICU